Glucocorticosteroids Modify Langerhans Cells To Produce TGF-b and Expand Regulatory T Cells
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Glucocorticosteroids modify Langerhans cells to produce TGF-β and expand regulatory T cells.
Although glucocorticosteroids (GCSs) have been used for many decades in transplantation and (auto)inflammatory diseases, the exact mechanisms responsible for their immunosuppressive properties are not fully understood. The purpose of this study was to characterize the effects of oral GCSs on the cutaneous immune response. We analyzed, by immunofluorescence staining and quantitative RT-PCR, resi...
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تاریخ انتشار 2010